Hello John and Doves,
The country is being told to prepare to distribute a
COVID-19 vaccine by November 1.
I was not aware of the shipping/storage
requirements for the mRNA type vaccines. WOW.
The CDC director is asking state governments to
wave requirements for building distribution sites.
Russia and China have already approved their
COVID-19 vaccines WITHOUT any human testing.
There are 4 possible candidates for a vaccine -
AstraZeneca has one (Oxford University), Moderna,
Pfizer, and BioNTech. All have started the phase 3
trials.
https://www.cidrap.umn.edu/news-perspective/2020/09/third-covid-vaccine-candidate-starts-phase-3-trial-us
Third
COVID vaccine candidate starts phase 3 trial in US |
CIDRAP
AstraZeneca: A 'recombinant viral vector'
vaccine. "This vaccine candidate uses a weakened
version of a common-cold virus that encodes instructions
for making proteins from the novel coronavirus to build
immunity."
https://news.yahoo.com/factbox-astrazenecas-potential-coronavirus-vaccine-111651409.html
Factbox:
AstraZeneca's potential coronavirus vaccine
The U.S. has granted $1.2 billion to their vaccine
research. Can produce 2 billion doses per
year. A two-dose regimen is anticipated.
Moderna: A mRNA vaccine. The
U.S. has granted $995 million to their vaccine
research. The CEO is worth $2.1 billion now. This
is an mRNA vaccine. This vaccine
requires a storage temperature of negative 4 degrees
Fahrenheit. Moderna can produce
about 1 billion doses per year.
Pfizer: A mRNA vaccine. This
vaccine requires a storage temperature of negative 94
degrees Fahrenheit.
BioNTech: A mRNA vaccine. This
vaccine requires a storage temperature of negative
94 degrees Fahrenheit.
Water freezes at 32 degrees Fahrenheit, 0
degrees Celsius.
Shipping of these mRNA vaccines will
require special shipping containers to provide these
temperatures. Getting these vaccines to third
world countries and remote areas will be a challenge.
"The vaccines would be making a tedious
journey, passing through some of the coldest
temperatures on Earth, before arriving at a clinic to
you. Long parallel aisles flanked by columns of
nearly two-meter tall freezers, each set at -80
degrees Celsius (-112 Fahrenheit), is where some of
the COVID-19 vaccines will be making a pit stop before
arriving at your doorstep. The huge facility -
the size of a soccer field - is one of the two freezer
farms that US logistics firm UPS is building to store
millions of doses of cornavirus vaccines and promptly
ship them across the world...The facilities, being
built close to UPS air cargo huts in the United States
and Germany, will together house 600 freezers, each
capable of storing 48,000 vials of vaccine. The
deep-freezers are being set up to store the more
fragile vaccines, including those that are based on
messenger RNA (mRNA) to produce vial proteins in the
body."
"Once ready, vaccines will leave the
laboratory in specialized, well-insulated boxes,
filled with dry ice or frozen carbon dioxide.
The boxes will be brought to one of the freezer farms,
where they would be carefully opened on a soft
stretcherlike table and stored in freezers. "You
would not be able to operate the freezer farms without
personal protective equipment (PPE). So, our
people are supplied with the right gear, like specific
gloves and goggles to be able to handle the products
inside,...It's not a temperature that you'll be able
to walk into."
"Base on instructions or orders from
customers, the vaccines would be put back in insulated
boxes filled with dry ice, capable of maintaining an
ideal temperature for up to 96 hours. Depending
on hos stringent specifications will be, the repacking
will take place in a room with temperature as low as
-20 degrees Celsius or one with temperatures ranging
from 2 degrees to 8 degrees Celsius - the ideal
storage temperature range for most vaccines - to
ensure the shots are not compromised."
"The vaccines will then be shipped by air
while ensuring they remain stable. UPS says it
would be able to provide overnight delivery to almost
any part of the world thanks to the proximity of its
freezer farms in Louisville, in the US state of
Kentucky, and the Venlo-Roermond area of the
Netherlands, to air hubs. The firm is also
setting up deep-freeze units in some places, including
in Frankfurt and the UK. With COVID-19 vaccines
being developed at an unprecedented pace, there is
hardly any data available on their fragility or
stability....Some experts say the first shipments of
the shots would need to be transported at "vaccine
untypical" conditions of -20 degrees Celsius, if not
at -80 degrees - a major challenge for freight
companies." Still much logistically to be
hammered out by UPS, the vaccine makers, governments,
health departments.
mRNA vaccines "trick" the body into making
some of the viral proteins itself.
"To produce an mRNA vaccine, scientists
produce a synthetic version of the mRNA that a virus
uses to build its infectious proteins. This mRNA is
delivered into the human body, whose cells read it as
instruction to build that viral protein, and therefore
create some of the virus's molecules themselves...The
immune system then detects these viral proteins and
starts to produce a defensive response to them....Because
mRNA vaccines are only now beginning to be tested in
humans, there are a lot of fairly basic unknowns
which can only be answered through human trials."
https://horizon-magazine.eu/article/five-things-you-need-know-about-mrna-vaccines.html
Five
things you need to know about: mRNA vaccines |
Horizon: the EU Research & Innovation magazine |
European Commission
RNA vaccines are faster and cheaper to
produce than traditional vaccines - allowing for
mass immunization programs. They can be
delivered in various ways: needle-syringe
injections, needle-free into the skin, nasal spray.
The drawbacks: mRNA can elicit an
unintended immune reaction, the RNA has to be placed
inside of a larger molecule to prevent it from being
broken down; the vaccines need to be frozen or
refrigerated; mRNA can possibly cause an autoimmune
reaction or inflammation.
And this won't be one 'shot' of vaccine -
the CDC is planning on two inoculations: a Vaccine A
and a Vaccine B.
Pfizer and BioNTech are hoping to have drug
approval as early as October. With 100 million
doses ready by the end of 2020. The USDA could
approve these with the 'emergency use authorization'.
The race for a vaccine is pushing the
research and testing to the limit as billions of
dollars are being paid out to various companies around
the world.
Countries all around the world have
contracts and have already purchased millions of
vaccines. All are hoping for vaccines by the end
of the year or early 2021. Example:
Australia has deals with vaccine companies to receive
3.8 million doses in January, February 2021.
Things can only return to 'normal' if THEY get us all
vaccinated. Things will NEVER return to normal.
Help
Wanted: Volunteers for COVID Vaccine Trials
Come Hell or high water, THEY are going to get people
vaccinated. And they are going to get vaccines
approved even before phase 3 is completed! Even
if they have multiple excellent treatments available
or numbers of sick people keep dropping.
Billions have been invested, billions have been
made.
Pray for the peace of Jerusalem!
Maranatha!
Chance