Was Jesus the only one who resisted unto blood, striving against sin?

Hebrews 12:4 Ye have not yet resisted unto blood, striving against sin.

Was this while he was being tempted, while in the garden of Gethsemane?

Luke 22:39 And he came out, and went, as he was wont, to the mount of Olives; and his disciples also followed him.

  40 And when he was at the place, he said unto them, Pray that ye enter not into temptation.

  41 And he was withdrawn from them about a stone’s cast, and kneeled down, and prayed,

  42 Saying, Father, if thou be willing, remove this cup from me: nevertheless not my will, but thine, be done.

  43 And there appeared an angel unto him from heaven, strengthening him.

  44 And being in an agony he prayed more earnestly: and his sweat was as it were great drops of blood falling down to the ground.