The structure that occupies the spot referred to in the below scripture is the Great Pyramid.  Therefore there has been much
speculation concerning the Great Pyramid and Bible prophecy.

"In that day shall there be an altar to the Lord in the midst of the land of Egypt, and a pillar at the border thereof to the Lord. And it
shall be for a sign and for a witness unto the Lord of hosts in the land of Egypt: for they shall cry unto the Lord because of the 
oppressors, and he shall send them a saviour, and a great one, and he shall deliver them." Isaiah 19: 19,20

"Which hast set signs and wonders in the land of Egypt, even unto this day…" Jeremiah 32:20a

Ever since I saw this article and Bible Code in 2004, I have been convinced Joseph built the Great Pyramid.  (See link for Bible Code
matrix and article):

http://ad2004.com/Biblecodes/Hebrewmatrix/pyramidspt1.html

"Also in the matrix, I give a hint of "who built it", at least for the Great Pyramid. There are ancient writings called the "Works of Joseph" 
which are supposedly from the Joseph in the Bible. He became second in command to the pharaoh and gathered up and stored grains 
during the 7 bountiful years, and then sold the grain during the 7 years of intense famine over all the earth. The Works of Joseph state 
that he instituted the pyramids project as a sort of huge public works project to put people to labor during the 7 years of famine.