Hello John and Doves,
So much for taking a year to 18 months to have a properly tested vaccine! Here's one that could be available by this fall.
"A novel coronavirus vaccine that received funding from the Bill and Melinda Gates Foundation has begun human trials. The INO-4800 DNA vaccine from Inovio has shown promise in preclinical trials, and the conclusions of Phase 1 study will be ready this summer. If successful, the vaccine could be ready for emergency use as soon as this fall."
One human trial started in the U.S. and one in China. The FDA approved an application from Inovio Pharmaceuticals under their program: Investigational New Drug.
As the name implies, this is a DNA vaccine and has worked well in the animal testing. Producing a large immune response with antibodies persisting over time.This drug has a "specifically engineered genetic structure" that's injected into the human body. https://bgr.com/2020/04/07/coronavirus-vaccine-phase-1-trial-for-bill-gates-backed-ino-4800/
Bill Gates-backed coronavirus vaccine enters human trial phase – BGR
In the U.S. 40 volunteers were selected for the inoculations in Phase 1.
So what is a DNA vaccine? Basically, it's a vaccine that is used to inject DNA into an animal system -example: horse, human, etc. It is a vaccine made by 'the injection with genetically engineered plasmid containing the DNA sequence encoding the antigen against which an immune response is sought so cells directly produce an antibody, producing a protective immunological response." https://en.wikipedia.org/wiki/DNA_vaccination
DNA vaccination - Wikipedia
Plasmids are small molecules of DNA that are not associated with chromosomes that can replicate independently; commonly found in bacteria. This DNA can be engineered to match an antigen one wants in a vaccine. The DNA contains a particular antigen's coding sequences (in this case, the antigen is the coronavirus SARS-CoV-2) - once this coding sequence is in the tissue, this antigen is produced in large enough quantities by the plasmid to produce a strong immune response. This antigen looks like and mimics the coronavirus. So the body starts the production of specific antibodies.
DNA vaccines are cost-efficient to produce, have a long shelf-life, are easy to manufacture, are safe to handle, have good biocompatibility (appear clinically safe); and specifically target what the vaccine is being made against. All of this makes these types of vaccines a good possibility for a future COVID-19 vaccine. Maybe even being available much sooner that a year to 18 months.
And Bill Gates is waiting in the wings - ready to mass produce the top one or two vaccines! To get these out to us ASAP! https://www.businessinsider.com/bill-gates-factories-7-different-vaccines-to-fight-coronavirus-2020-4
Bill Gates is helping fund factories for 7 coronavirus vaccine candidates - Business Insider
Currently there are no approved DNA vaccines for human use. There is a vaccine approved for West Nile Virus in horses that is a DNA vaccine.
There is also a research group working on a nasal spray for this coronavirus that's also DNA- based.
"Researchers at University of Waterloo are developing a DNA-based vaccine for COVID-19 that will be delivered through a nasal spray. This vaccine will be engineered to mimic SARS-CoV-2, that virus which causes COVID-19...Once it gets into those cells they will construct what looks like and mimics the (COVID-19) virus and that will then allow for an antibody response against actual infections." https://www.therecord.com/news-story/9954697-uw-researchers-work-to-develop-dna-based-vaccine-for-covid-19/
UW researchers work to develop DNA-based vaccine for COVID-19 | TheRecord.com
The nasal spray will trigger an immune response in the nasal cavities. They are hoping to have preclinical trials completed by April 2021.
So now we have the rush to produce a vaccine for us.
We'll be keeping a close eye on these tests and trials over the coming months. https://clinicaltrials.gov/ct2/results?cond=COVID+OR+coronavirus+OR+SARS-CoV-2&term=remdesivir&cntry=&state=&city=&dist=&Search=Search
Search of: remdesivir | COVID OR coronavirus OR SARS-CoV-2 - List Results - ClinicalTrials.gov
Pray for the peace of Jerusalem!
Maranatha!
Chance