The arrival of the last Pope, who is the False Prophet that will lead the world-wide "falling away" before the revealing of the anti-Christ, marks the opening of the First Seal.
Revelation 6:2 (Seal #1)
"I looked, and behold a white horse. He who sat on it had a bow; and a crown was given to him, and he went out conquering and to conquer.
This is the description of the last Pope, who is the False Prophet who will lead the world-wide apostasy or "falling away' from the true God of the Scriptures who is Jesus Christ just before the appearance of the anti-Christ. The "white horse" is the Roman Catholic Church on whose throne the last Pope sits. The "bow" is his authority of the Papacy, and the "crown" is his office of the Papacy. The last Pope False Prophet will travel the world "to conquer" the world into believing and following his false teachings, and lead the world-wide "falling away".
2 Thessalonians 2:3
".........that Day will not come unless the falling away comes first, and the man of sin is revealed......so that he sits as God in the temple of God, showing himself that he is God."