Your posts regarding unsaved loved ones really touched my heart.  I know how you feel;  it's so hard to think of them being "left behind",  facing the horrible time of the Tribulation.  They're so focused on this world that is passing away since the world looks so glamorous,  though it's really a pile of ashes.
 
I hope they will be saved before the rapture !!  But if not,  we know from the Bible that MANY people will be saved after it takes place.  Though they might give up their physical life, as did many Christians over the centuries.
 
Revelation chapter 7 shows us a "great multitude that no one could number...who (have) come out of the Great Tribulation and washed their robes and made them white in the blood of the Lamb."
 
Judy,  you're so right that we cannot give up on any of them.  The Lord cares about them even more than we do,  and I know He will hear our prayers.